Cardiovascular Diseases

Cardiovascular disease (CVD) is the leading cause of death in the developed as well as in the developing world. CVD continues to be the leading cause of death in the US, and 880,574 people died from CVD in 2016. CVD cause one third of all deaths in China, and 4,344,334 people died from CVD in 2016.

Our experienced team across computation chemistry, medicinal chemistry, bioscience, DMPK, pharmacologist and toxicologist deliver an integrated and flexible discovery. We can provide service as following in cardiovascular disease (CVD):

• Target proposal

• Target validation

• DEL screening

• Structure based design

• Biochemical assays development

• Screening and lead identification

• In vitro and in vivo pharmacodynamics

• Pharmacokinetics and pharmacodynamics (PK/PD) 

• Drug metabolism and pharmacokinetics (DMPK)

• Non-GLP toxicology

• Toxicokinetics (TK)

• AMES

• IND application and clinical study